Symptoms may include nervousness, irritability, anger, and anxiety, insomnia, and rapid breathing. You may experience pain, swelling, redness, itching, or rash at the injection site.

Flumazenil may cause panic attacks in patients with a history of panic disorder. Panic attacks include a feeling of sudden fear or worry, difficult or fast breathing, rapid heartbeat, flushing, and anxiety. Your healthcare professional should monitor you for the return of these overdose symptoms while you are being treated with flumazenil. Symptoms include slowed or difficult breathing (respiratory depression). Hypoventilation occurs when the lungs are slowed and are no longer able to perform adequate gas exchange. Your healthcare provider will monitor you for re-sedation following administration of flumazenil. You may experience serious sedation or stupor after administration of flumazenil. Seizures and convulsions are more common if you have taken benzodiazepines for a long period of time. Serious side effects have been reported with flumazenil including the following: Ask your doctor or pharmacist for more information. This is not a complete list of flumazenil drug interactions. Flumazenil reverses this activity, which may lead to convulsions, especially when drug overdose has occurred with medications that cause seizures. Benzodiazepines have anti-seizure activity. In the case of drug overdose with multiple drugs, flumazenil should be used with caution. Flumazenil can potentially interact with other central nervous system depressants by blocking their effect.

tricyclic antidepressants such as trimipramine (Surmontil), amitriptyline (Elavil), nortriptyline ( Pamelor, Aventyl), protriptyline ( Vivactil), and clomipramine (Anafranil)ĭrug interactions with other central nervous system depressants such as certain narcotics have not been studied specifically.

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Flumazenil antidote